Back and neck pain can make every movement feel like work. When rest, activity changes, and medication are not enough, image-guided spinal injections can calm inflamed nerves, confirm the true source of pain, and help you move again.
This guide explains the three most common injections offered at Regional Brain & Spine, how they differ, what to expect, and what comes next if relief is temporary.
A Quick Visual in Words
Understanding where the medicine goes makes everything clearer:
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Facet joint – Two small joints at the back of each vertebra that guide motion. Think of them as tiny hinges.
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Medial branch nerve – A thin wire-like nerve that carries pain signals from each facet joint to the spinal cord.
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Epidural space – A narrow sleeve around the spinal nerves, where medication spreads along irritated nerve roots.
Each injection targets a different structure and type of pain.
What Each Injection Treats
Facet Joint Injection
Medication is placed inside the facet joint.
Best for:
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Achy neck or low-back pain
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Pain worse with bending backward or twisting
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Minimal arm or leg pain
These injections reduce joint inflammation and help confirm the facet joint as the pain source.
Medial Branch Block
Local anesthetic is placed on the medial branch nerves that supply the facet joints.
Purpose:
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Diagnostic – confirms whether the facet joints are causing pain
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Short-term relief only
If two well-performed blocks provide clear pain relief, you may qualify for radiofrequency ablation (RFA), which provides longer-lasting relief.
Epidural Steroid Injection
Anti-inflammatory medicine is placed into the epidural space to calm irritated spinal nerves.
Best for:
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Herniated discs
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Spinal stenosis
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Sciatica or arm pain
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Pinched nerves
This is the preferred injection when pain travels down the arm or leg.
Who Performs These Procedures?
At Regional Brain & Spine, injections are performed by board-certified pain management physicians and fellowship-trained interventional specialists using live X-ray guidance (fluoroscopy) for accuracy and safety.
Advanced practice providers support evaluation, education, and follow-up.
What to Expect on Procedure Day
Before
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Imaging, medications, and allergies are reviewed
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Blood thinners managed safely
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Consent and nurse instructions
During
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Local numbing medication
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Thin needle guided by live X-ray
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Contrast dye confirms correct placement
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Most people feel pressure, not pain
After
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Short recovery
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Go home the same day
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Resume light activity within 24 hours
Steroid vs Non-Steroid Injections
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Steroid – reduces inflammation and prolongs relief (common in epidurals and facet injections)
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Non-steroid – local anesthetic only (used for medial branch blocks or when steroids are not advised)
Yes — facet injections can be done without steroids when diagnosis is the goal or steroids are contraindicated.
How Long Does Relief Last?
Facet Joint Injections
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Relief: hours to several months
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If short-lived, medial branch blocks → RFA
Medial Branch Blocks
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Relief: hours to 1–2 days
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Used to confirm facet-mediated pain
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Two positive blocks predict good response to RFA
Epidural Steroid Injections
For L4–L5 and sciatica-type pain:
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Many patients experience weeks to months of relief
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Results depend on disc size, stenosis, and nerve compression
What Happens If Relief Wears Off?
| If you had… | Next Step |
|---|---|
| Facet injection | Medial branch blocks → radiofrequency ablation |
| Epidural injection | Repeat epidural, therapy, medication changes, or surgical evaluation |
| No benefit | Options include nerve stimulation, basivertebral nerve ablation, or spinal cord stimulation |
Learn more about image-guided injections in Cape Girardeau on our site.
Safety and Timing
Common side effects:
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Temporary soreness
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Numbness
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Mild dizziness
Rare risks:
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Infection
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Bleeding
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Nerve irritation
Spacing rules
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Medial branch blocks: usually 1–2 weeks apart
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Epidural steroids: usually 2–4 weeks apart
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Total steroid use is limited for safety
Insurance and Cost
Most insurance plans and Medicare cover injections when:
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Symptoms and imaging match
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Conservative care has been tried
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Documentation meets medical necessity
Our team verifies benefits and handles prior authorizations before scheduling.
How to Get the Most from Your Injection
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Track pain relief and activity for one week
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Walk and move as tolerated
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Use relief to rebuild strength and posture
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Remember: injections support recovery — they do not replace it
Why Choose Regional Brain & Spine?
We provide coordinated care across:
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Pain management
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PM&R
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Neurosurgery
We start conservatively, use precise image-guided injections, and advance only when the next step truly makes sense.
We serve Cape Girardeau, Farmington, and Dexter, with specialized options such as facet joint injections in Farmington.
Summary
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Facet injections treat joint-based spine pain
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Medial branch blocks confirm facet pain and guide radiofrequency ablation
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Epidural steroid injections treat pinched nerves and sciatica
Relief may last from hours to months, but when paired with rehabilitation and a clear treatment plan, these injections can restore mobility and reduce pain meaningfully.
Regional Brain & Spine will help you choose the right injection at the right time, so you can get back to moving with confidence.

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